Codon Pair Deoptimization (CPD)-Attenuated PRRSV-1 Vaccination Exhibit Immunity to Virulent PRRSV Challenge in Pigs

Codon Pair Deoptimization (CPD)-Attenuated PRRSV-1 Vaccination Exhibit Immunity to Virulent PRRSV Challenge in Pigs

Commercially used porcine respiratory and reproductive syndrome (PRRS) modified live virus (MLV) vaccines provide limited protection with heterologous viruses, can revert back to a virulent form and they tend to recombine with circulating wild-type strains. Codon pair deoptimization (CPD) is an adva...

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Bibliographic Details
Main Authors: Min-A Lee, Su-Hwa You, Usharani Jayaramaiah, Eun-Gyeong Shin, Seung-Min Song, Lanjeong Ju, Seok-Jin Kang, Sun Hee Cho, Bang-Hun Hyun, Hyang-Sim Lee
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Vaccines
Subjects:
porcine reproductive and respiratory syndrome virus type (PRRSV)-1
codon pair deoptimization (CPD)
ORF7 gene
vaccine
Online Access:https://www.mdpi.com/2076-393X/11/4/777

Internet

https://www.mdpi.com/2076-393X/11/4/777

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