Induction of Filopodia During Cytomegalovirus Entry Into Human Iris Stromal Cells

Many viruses exploit thin projections of filopodia for cell entry and cell-to-cell spread. Using primary cultures of human iris stromal (HIS) cells derived from human eye donors, we report a significant increase in filopodia formation during human cytomegalovirus (HCMV) infection. Using confocal mic...

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Bibliographic Details
Main Authors: Kenneth Chang, Hardik Majmudar, Ritesh Tandon, Michael V. Volin, Vaibhav Tiwari
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.834927/full