Expression of the Stem Cell Factor Nestin in Malignant Pleural Mesothelioma Is Associated with Poor Prognosis.

The epithelioid and sarcomatoid histologic variants of malignant pleural mesothelioma (MPM) can be considered as E- and M-parts of the epithelial-mesenchymal transition (EMT) axis; the biphasic being an intermediate. EMT is associated with an increase of stem cell (SC) traits. We correlated the neur...

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Bibliographic Details
Main Authors: Svenja Thies, Martina Friess, Lukas Frischknecht, Dimitri Korol, Emanuela Felley-Bosco, Rolf Stahel, Bart Vrugt, Walter Weder, Isabelle Opitz, Alex Soltermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4589394?pdf=render