MEG3 targets miR-184 and Wnt/β-catenin and modulates properties of osteosarcoma

Recent studies indicate that MEG3, a long non-coding RNA (lncRNA) and microRNA-184 (miR-184) are abnormally expressed in osteosarcoma (OS). To this end, we show here that MEG3 negatively regulates the expression of miR-184 and down-stream effectors of WNT/β-catenin pathway including β-catenin, T-cel...

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Bibliographic Details
Main Authors: Liang Li, SiBiao Pei, Na Sun
Format: Article
Language:English
Published: IMR Press 2020-06-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/25/10/10.2741/4884