Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion

ABSTRACT Antibiotic resistance is rapidly spreading via the horizontal transfer of resistance genes in mobile genetic elements. While plasmids are key drivers of this process, few integrative phages encode antibiotic resistance genes. Here, we find that phage-plasmids, elements that are both phages...

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Bibliographic Details
Main Authors: Eugen Pfeifer, Rémy A. Bonnin, Eduardo P. C. Rocha
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.01851-22