Is there a causal relationship between executive function and liability to mental health and substance use? A Mendelian randomization approach

Poorer performance in tasks testing executive function (EF) is associated with a range of psychopathologies such as schizophrenia, major depressive disorder (MDD) and anxiety, as well as smoking and alcohol consumption. We used two-sample bidirectional Mendelian randomization to examine whether thes...

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Bibliographic Details
Main Authors: Sabrina M. I. Burton, Hannah M. Sallis, Alexander S. Hatoum, Marcus R. Munafò, Zoe E. Reed
Format: Article
Language:English
Published: The Royal Society 2022-12-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.220631