Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination

Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination

Abstract Background Although metastasis is the foremost cause of cancer-related death, a specialized mechanism that reprograms anchorage dependency of solid tumor cells into circulating tumor cells (CTCs) during metastatic dissemination remains a critical area of challenge. Methods We analyzed blood...

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Bibliographic Details
Main Authors: Hyunbin D. Huh, Yujin Sub, Jongwook Oh, Ye Eun Kim, Ju Young Lee, Hwa-Ryeon Kim, Soyeon Lee, Hannah Lee, Sehyung Pak, Sebastian E. Amos, Danielle Vahala, Jae Hyung Park, Ji Eun Shin, So Yeon Park, Han Sang Kim, Young Hoon Roh, Han-Woong Lee, Kun-Liang Guan, Yu Suk Choi, Joon Jeong, Junjeong Choi, Jae-Seok Roe, Heon Yung Gee, Hyun Woo Park
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Molecular Cancer
Online Access:https://doi.org/10.1186/s12943-023-01753-7

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https://doi.org/10.1186/s12943-023-01753-7

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