Systemic Homologous Neutralizing Antibodies Are Inadequate for the Evaluation of Vaccine Protective Efficacy against Coinfection by High Virulent PEDV and PRRSV

Systemic Homologous Neutralizing Antibodies Are Inadequate for the Evaluation of Vaccine Protective Efficacy against Coinfection by High Virulent PEDV and PRRSV

ABSTRACT G2 porcine epidemic diarrhea virus (G2 PEDV) and highly pathogenic porcine reproductive and respiratory syndrome virus 2 (HP-PRRSV2) are two of the most prevalent swine pathogens in China’s swine herds, and their coinfection occurs commonly. Several PED and PRRS vaccines have been utilized...

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Bibliographic Details
Main Authors: Ming Qiu, Shubin Li, Mengxue Ye, Jixiang Li, Zhe Sun, Xinshuai Li, Yulin Xu, Yanzhao Xiao, Chen Li, Binghui Feng, Hong Lin, Wanglong Zheng, Xiuling Yu, Kegong Tian, Jianzhong Zhu, Nanhua Chen
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
porcine epidemic diarrhea virus (PEDV)
porcine reproductive and respiratory syndrome virus (PRRSV)
chimeric vaccine
systemic homologous neutralizing antibodies (shnAbs)
protective efficacy
neonatal piglet
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02574-21

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https://journals.asm.org/doi/10.1128/spectrum.02574-21

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