Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2
Abstract Guanylate-binding proteins (GBPs) are a group of GTPases that are induced by interferon- $$\gamma$$ γ and are crucial components of cell-autonomous immunity against intracellular pathogens. Here, we examine murine GBP2 (mGBP2), which we have previously shown to be an essential effector prot...
Main Authors: | Jennifer Loschwitz, Nora Steffens, Xue Wang, Moritz Schäffler, Klaus Pfeffer, Daniel Degrandi, Birgit Strodel |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-27520-8 |
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