An Improved Genome-Wide Polygenic Score Model for Predicting the Risk of Type 2 Diabetes

Polygenic risk score (PRS) has been shown to be predictive of disease risk such as type 2 diabetes (T2D). However, the existing studies on genetic prediction for T2D only had limited predictive power. To further improve the predictive capability of the PRS model in identifying individuals at high T2...

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Bibliographic Details
Main Authors: Wei Liu, Zhenhuang Zhuang, Wenxiu Wang, Tao Huang, Zhonghua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.632385/full