Design of a Randomized Controlled Clinical Study of tissue-engineered osteogenic materials using bone marrow-derived mesenchymal cells for Maxillomandibular bone defects in Japan: the TEOM study protocol

Abstract Background Maxillomandibular bone defects arise from maxillofacial injury or tumor/cyst removal. While the standard therapy for bone regeneration is transplantation with autologous bone or artificial bone, these therapies are still unsatisfactory. Autologous bone harvesting is invasive and...

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Main Authors: Shinobu Shimizu, Shuhei Tsuchiya, Akihiro Hirakawa, Katsuyoshi Kato, Masahiko Ando, Masaaki Mizuno, Masashi Osugi, Kazuto Okabe, Wataru Katagiri, Hideharu Hibi
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Oral Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12903-019-0753-1