Otilonium bromide boosts antimicrobial activities of colistin against Gram-negative pathogens and their persisters
The drug otilonium bromide restores the activity of colistin against colistinresistant Gram-negative bacteria in vitro and in a mouse infection model, suggesting that this combination may restore the value of colistin in treatment of antibiotic resistant disease.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03561-z |