Effects of Caspase Inhibitors on Hematopoietic Engraftment after Short-Term Culture

The induction of apoptosis during cytokine-induced proliferation of hematopoietic stem and progenitor cells (HSPC) may result in the loss of hematopoietic function. We tested the ability of several caspase inhibitors to maintain transplantation potential of mouse HSPC during in vitro culture. HSPC w...

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Bibliographic Details
Main Authors: Anne Wiesmann, A. Elena Searles, L. Jeanne Pierce, Gerald J. Spangrude
Format: Article
Language:English
Published: SAGE Publishing 2002-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000002783985800