Circ_0000396 suppresses the proliferation and inflammation of rheumatoid arthritis synovial fibroblasts by targeting miR-574-5p/RSPO1 axis

Abstract Background Circular RNAs (circRNAs) are important regulators on the onset and progression of rheumatoid arthritis (RA). Our purpose is to explore the role and underpin mechanism of circ_0000396 in RA progression. Methods RA patients (n = 39) and healthy volunteers (n = 33) were recruited fr...

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Bibliographic Details
Main Authors: Hongchao Yu, Jin Yang, Kun Chen, Wulin Kang, Fengfeng Zhu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-04117-5