Genomic Assembly of Clinical Candida glabrata (Nakaseomyces glabrata) Isolates Reveals within-Species Structural Plasticity and Association with In Vitro Antifungal Susceptibility

Genomic Assembly of Clinical Candida glabrata (Nakaseomyces glabrata) Isolates Reveals within-Species Structural Plasticity and Association with In Vitro Antifungal Susceptibility

ABSTRACT The opportunistic human pathogen Candida glabrata has become an increasingly important threat to human health, with infections globally characterized by high mortality rates and multidrug resistance. To face this threat, more efficient diagnostic and therapeutic approaches are required, und...

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Bibliographic Details
Main Authors: Irene Stefanini, Emily Stoakes, Houdini H. T. Wu, Li Xu-McCrae, Abid Hussain, John Moat, Christopher G. Dowson, Miruna D. David, Chrystala Constantinidou
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
Candida glabrata
antifungals
antimicrobial resistance
genomics
population genetics
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01827-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01827-22

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