Survival impact and risk factors of skeletal muscle loss during first-line EGFR-TKIs therapy in advanced lung adenocarcinoma patients

Abstract Purpose The impact of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) on muscle mass in individuals with advanced lung cancer has yet to be fully delineated. This study aimed to examine the dynamics of skeletal muscle mass during EGFR-TKIs targeted therapy, elucida...

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Bibliographic Details
Main Authors: Xin Nie, Mingzhu Zou, Chenhui Song, Ping Zhang, Di Ma, Di Cui, Gang Cheng, Lin Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-025-13775-z