Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cells

Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cells

Introduction and Objectives: Cholangiocarcinoma (CCA) is characterized by early distant invasion and metastasis, whereas the underlying mechanism is still obscure. Increasing evidence shows that collagen type Ι alpha 1 (COL1A1) is a gene associated with the progression of multiple diseases. Here, we...

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Bibliographic Details
Main Authors: Shuguang Pan, Ying Hu, Lang Gan, Jiejuan Lai, Ping Zheng, YuJun Zhang, Ling Shuai, Yan Jiang, Mo Chen, Junping Wang, Yu He
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Annals of Hepatology
Subjects:
Cholangiocarcinoma
Metastasis
MMP2
COL1A1
Integrin alpha Ⅴ
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268123003824

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http://www.sciencedirect.com/science/article/pii/S1665268123003824

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