Dl-3-n-Butylphthalide Reduced Neuroinflammation by Inhibiting Inflammasome in Microglia in Mice after Middle Cerebral Artery Occlusion

Dl-3-n-Butylphthalide Reduced Neuroinflammation by Inhibiting Inflammasome in Microglia in Mice after Middle Cerebral Artery Occlusion

The inflammatory response is one of the key events in cerebral ischemia, causing secondary brain injury and neuronal death. Studies have shown that the NLRP3 inflammasome is a key factor in initiating the inflammatory response and that Dl-3-n-butylphthalide (NBP) can attenuate the inflammatory respo...

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Bibliographic Details
Main Authors: Mengdi Liu, Haoran Zheng, Ze Liu, Yiyan Guo, Shuhong Wang, Yaohui Tang, Hengli Tian, Zhijun Zhang, Guoyuan Yang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Life
Subjects:
dl-3n-butylphthalide
ischemic stroke
microglia
NLRP3 inflammasome
Online Access:https://www.mdpi.com/2075-1729/12/8/1244

Internet

https://www.mdpi.com/2075-1729/12/8/1244

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