Leishmania donovani induced increase in macrophage Bcl-2 favors parasite survival

Members of the Bcl-2 family are major regulators of apoptosis in mammalian cells and hence infection-induced perturbations in their expression could result into elimination of the parasites or creation of a niche favoring survival. In this investigation, we uncover a novel role of host Bcl-2 in sust...

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Bibliographic Details
Main Authors: Rajeev Kumar Pandey, Sanjana Mehrotra, Smriti Sharma, Ramachandra Subbaraya Gudde, Shyam Sundar, Chandrima Shaha
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00456/full