Immunogenicity and Protective Efficacy of Baculovirus-Expressed SARS-CoV-2 Envelope Protein in Mice as a Universal Vaccine Candidate

Immunogenicity and Protective Efficacy of Baculovirus-Expressed SARS-CoV-2 Envelope Protein in Mice as a Universal Vaccine Candidate

The envelope (env) protein of SARS-CoV-2, a pivotal component of the viral architecture, plays a multifaceted role in viral assembly, replication, pathogenesis, and ion channel activity. These features make it a significant target for understanding virus–host interactions and developing vaccines to...

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Bibliographic Details
Main Authors: Tuba Çiğdem Oğuzoğlu, Alireza Hanifehnezhad, Saber Delpasand Khabbazi, İlke Karayel-Hacıoğlu, Onur Kaynarcalıdan, Zehra Fırat, Nazlıcan Filazi, Eda Erdem-Şahinkesen, Buket Gül, Muhammed Cesim Karabulut, Enes Koba, Ece Adıgüzel, Elif İrem Şenlik, Emrah Korkulu, Cansu Demirden, İlker Şahinkesen, Ahmet Ceylan, Hacer Muratoğlu, Sevil Vural, Zihni Demirbağ, Aykut Özkul
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Vaccines
Subjects:
SARS-CoV-2
envelope protein
recombinant
baculovirus
Online Access:https://www.mdpi.com/2076-393X/12/9/977

Internet

https://www.mdpi.com/2076-393X/12/9/977

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