Role of glutamic acid decarboxylase 67 in regulating cortical parvalbumin and GABA membrane transporter 1 expression: Implications for schizophrenia

Markers of GABA neurotransmission are altered in multiple regions of the neocortex in individuals with schizophrenia. Lower levels of glutamic acid decarboxylase 67 (GAD67) mRNA and protein, which is responsible for most cortical GABA synthesis, are accompanied by lower levels of GABA membrane trans...

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Detalhes bibliográficos
Principais autores: Allison A. Curley, Stephen M. Eggan, Matt S. Lazarus, Z. Josh Huang, David W. Volk, David A. Lewis
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2013-02-01
coleção:Neurobiology of Disease
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996112003464