Hybridization and amplification rate correction for affymetrix SNP arrays

<p>Abstract</p> <p>Background</p> <p>Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimatio...

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Bibliographic Details
Main Authors: Wang Quan, Peng Peichao, Qian Minping, Wan Lin, Deng Minghua
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Medical Genomics
Subjects:
Online Access:http://www.biomedcentral.com/1755-8794/5/24