CDC50 Orthologues in Plasmodium falciparum Have Distinct Roles in Merozoite Egress and Trophozoite Maturation

CDC50 Orthologues in Plasmodium falciparum Have Distinct Roles in Merozoite Egress and Trophozoite Maturation

ABSTRACT In model organisms, type IV ATPases (P4-ATPases) require cell division control protein 50 (CDC50) chaperones for their phospholipid flipping activity. In the malaria parasite Plasmodium falciparum, guanylyl cyclase alpha (GCα) is an integral membrane protein that is essential for release (e...

Full description

Bibliographic Details
Main Authors: Avnish Patel, Stephanie D. Nofal, Michael J. Blackman, David A. Baker
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mBio
Subjects:
CDC50
P4-ATPase
Plasmodium falciparum
malaria
signal transduction
Online Access:https://journals.asm.org/doi/10.1128/mbio.01635-22

Internet

https://journals.asm.org/doi/10.1128/mbio.01635-22

Similar Items