The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors

The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors

Protein phosphatase 2A (PP2A) is a highly complex heterotrimeric Ser/Thr phosphatase that regulates many cellular processes. PP2A is dysregulated in several human diseases, including oncological pathology; interestingly, PP2A appears to be essential for controlling cell growth and may be involved in...

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Bibliographic Details
Main Authors: Laura Cucinotta, Alessia Filippone, Giovanna Casili, Marika Lanza, Valentina Bova, Anna Paola Capra, Raffaella Giuffrida, Cristina Colarossi, Dorotea Sciacca, Irene Paterniti, Salvatore Cuzzocrea, Michela Campolo, Emanuela Esposito
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
PP2A
PP2A inhibitors
cancer
brain tumors
GBM
CIP2A inhibition
Online Access:https://www.mdpi.com/1422-0067/23/24/15717

Internet

https://www.mdpi.com/1422-0067/23/24/15717

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