CXCL1-LCN2 paracrine axis promotes progression of prostate cancer via the Src activation and epithelial-mesenchymal transition

CXCL1-LCN2 paracrine axis promotes progression of prostate cancer via the Src activation and epithelial-mesenchymal transition

Abstract Background Mechanisms driving the progression of castration-resistant prostate cancer are believed to relate substantially to the tumor microenvironment. However, the cross-talks between tumor epithelial cell, stromal cells, and immune cells are yet to be fully elucidated. The present study...

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Bibliographic Details
Main Authors: Yongning Lu, Baijun Dong, Fan Xu, Yunze Xu, Jiahua Pan, Jiajia Song, Jin Zhang, Yiran Huang, Wei Xue
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Cell Communication and Signaling
Subjects:
Chemokine
Cytokine
Tumor cell migration
Tumor metastasis
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s12964-019-0434-3

Internet

http://link.springer.com/article/10.1186/s12964-019-0434-3

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