Nanomicelles of Radium Dichloride [<sup>223</sup>Ra]RaCl<sub>2</sub> Co-Loaded with Radioactive Gold [<sup>198</sup>Au]Au Nanoparticles for Targeted Alpha–Beta Radionuclide Therapy of Osteosarcoma

Nanomicelles of Radium Dichloride [<sup>223</sup>Ra]RaCl<sub>2</sub> Co-Loaded with Radioactive Gold [<sup>198</sup>Au]Au Nanoparticles for Targeted Alpha–Beta Radionuclide Therapy of Osteosarcoma

Alpha and beta particulate radiation are used for non-treated neoplasia, due to their ability to reach and remain in tumor sites. Radium-223 (<sup>223</sup>Ra), an alpha emitter, promotes localized cytotoxic effects, while radioactive gold (<sup>198</sup>Au), beta-type energy...

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Bibliographic Details
Main Authors: Bárbara Nayane Rosário Fernandes Souza, Elisabete Regina Fernandes Ramos Ribeiro, Aline Oliveira da Silva de Barros, Martha Sahylí Ortega Pijeira, Hericka Oliveira Kenup-Hernandes, Eduardo Ricci-Junior, Joel Félix Silva Diniz Filho, Clenilton Costa dos Santos, Luciana Magalhães Rebelo Alencar, Mohamed F. Attia, Sara Gemini-Piperni, Ralph Santos-Oliveira
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Polymers
Subjects:
alpha–beta therapy
bone cancer
radium-223 dichloride
radioactive gold nanoparticles
nanomicelles
Online Access:https://www.mdpi.com/2073-4360/14/7/1405

Internet

https://www.mdpi.com/2073-4360/14/7/1405

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