Resting State BOLD Variability Is Linked to White Matter Vascular Burden in Healthy Aging but Not in Older Adults With Subjective Cognitive Decline

Resting State BOLD Variability Is Linked to White Matter Vascular Burden in Healthy Aging but Not in Older Adults With Subjective Cognitive Decline

Background: Alzheimer’s disease (AD) is the leading cause of dementia. A lack of curative treatments and a rapidly aging global population have amplified the need for early biomarkers of the disease process. Recent advances suggest that subjective cognitive decline (SCD) may be one of the earliest s...

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Bibliographic Details
Main Authors: Vanessa Scarapicchia, Mauricio Garcia-Barrera, Stuart MacDonald, Jodie R. Gawryluk
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Human Neuroscience
Subjects:
signal variability
Alzheimer’s disease
subjective cognitive decline
cerebrovascular health
aging
biomarkers
Online Access:https://www.frontiersin.org/article/10.3389/fnhum.2019.00429/full

Internet

https://www.frontiersin.org/article/10.3389/fnhum.2019.00429/full

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