Proguanil Suppresses Breast Tumor Growth In Vitro and In Vivo by Inducing Apoptosis via Mitochondrial Dysfunction

Breast cancer, ranking as the second leading cause of female cancer-related deaths in the U.S., demands the exploration of innovative treatments. Repurposing FDA-approved drugs emerges as an expedited and cost-effective strategy. Our study centered on proguanil, an antimalarial drug, reveals notable...

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Bibliographic Details
Main Authors: Nehal Gupta, Marina Curcic, Sanjay K. Srivastava
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/5/872