DDX5/METTL3-METTL14/YTHDF2 Axis Regulates Replication of Influenza A Virus

DDX5/METTL3-METTL14/YTHDF2 Axis Regulates Replication of Influenza A Virus

ABSTRACT DEAD-box helicase 5 (DDX5), a member of the DEAD/H-box helicases, is known to participate in all aspects of RNA metabolism. However, its regulatory effect in antiviral innate immunity during replication of influenza virus remains unclear. Herein, we found that human DDX5 promotes replicatio...

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Bibliographic Details
Main Authors: Lingcai Zhao, Yongzhen Zhao, Qingzheng Liu, Jingjin Huang, Yuanlu Lu, Jihui Ping
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
DDX5
IFN-β
METTL3-METTL14/YTHDF2
antiviral immunity
influenza viruses
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01098-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01098-22

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