Sinonasal Stent Coated with Slow-Release Varnish of Chlorhexidine Has Sustained Protection against Bacterial Biofilm Growth in the Sinonasal Cavity: An In Vitro Study

Sinonasal Stent Coated with Slow-Release Varnish of Chlorhexidine Has Sustained Protection against Bacterial Biofilm Growth in the Sinonasal Cavity: An In Vitro Study

The aim of the study was to develop a sustained-release varnish (SRV) containing chlorhexidine (CHX) for sinonasal stents (SNS) to reduce bacterial growth and biofilm formation in the sinonasal cavity. Segments of SNS were coated with SRV-CHX or SRV-placebo and exposed daily to bacterial cultures of...

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Bibliographic Details
Main Authors: Alessandra Cataldo Russomando, Ronit Vogt Sionov, Michael Friedman, Irith Gati, Ron Eliashar, Doron Steinberg, Menachem Gross
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
bacteria biofilm
biofilm inhibition
chlorhexidine
chronic rhinosinusitis
nasal stent
<i>Pseudomonas aeruginosa</i>
Online Access:https://www.mdpi.com/1999-4923/13/11/1783

Internet

https://www.mdpi.com/1999-4923/13/11/1783

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