Effect of Neprilysin Inhibition for Ischemic Mitral Regurgitation after Myocardial Injury

Effect of Neprilysin Inhibition for Ischemic Mitral Regurgitation after Myocardial Injury

Angiotensin receptor neprilysin inhibitor (ARNI) treatment reduces functional mitral regurgitation (MR) to a greater extent than angiotensin receptor blocker (ARB) treatment alone, but the mechanism is unclear. We evaluated the mechanisms of how ARNI has an effect on functional MR. After inducing fu...

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Bibliographic Details
Main Authors: Sahmin Lee, Hyo-Sook Hwang, Naaleum Song, Geun-Hyung Kang, Kyoung-Hee Choi, Eunhye Ji, Jong-Min Song, Duk-Hyun Kang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
neprilysin
angiotensin receptor antagonists
mitral valve insufficiency
heart failure
heart ventricles
Online Access:https://www.mdpi.com/1422-0067/22/16/8598

Internet

https://www.mdpi.com/1422-0067/22/16/8598

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