Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function

Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function

Summary: Regulatory T cells (Tregs) are pivotal for immune suppression. Cellular metabolism is important for Treg homeostasis and function. However, the exact role of mitochondrial respiration in Tregs remains elusive. Mitochondrial transcription factor A (Tfam) is essential for mitochondrial respir...

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Bibliographic Details
Main Authors: Zheng Fu, Jian Ye, Joseph W. Dean, John W. Bostick, Samuel E. Weinberg, Lifeng Xiong, Kristen N. Oliff, Zongming E. Chen, Dorina Avram, Navdeep S. Chandel, Liang Zhou
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719307909

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http://www.sciencedirect.com/science/article/pii/S2211124719307909

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