γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice

γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice

Abstract Background Infection and sepsis are associated with brain white matter injury in preterm infants and the subsequent development of cerebral palsy. Methods In the present study, we used a neonatal mouse sepsis-induced white matter injury model to determine the contribution of different T cel...

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Bibliographic Details
Main Authors: Xiaoli Zhang, Eridan Rocha-Ferreira, Tao Li, Regina Vontell, Darakhshan Jabin, Sha Hua, Kai Zhou, Arshed Nazmi, Anna-Maj Albertsson, Kristina Sobotka, Joakim Ek, Claire Thornton, Henrik Hagberg, Carina Mallard, Jianmei W. Leavenworth, Changlian Zhu, Xiaoyang Wang
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Neuroinflammation
Subjects:
Sepsis
White matter injury
T lymphocytes
Behavior tests
Preterm
Online Access:http://link.springer.com/article/10.1186/s12974-017-1029-9

Internet

http://link.springer.com/article/10.1186/s12974-017-1029-9

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