The Role of Plasma Membrane Viscosity in the Response and Resistance of Cancer Cells to Oxaliplatin

The Role of Plasma Membrane Viscosity in the Response and Resistance of Cancer Cells to Oxaliplatin

Maintenance of the biophysical properties of membranes is essential for cell survival upon external perturbations. However, the links between a fluid membrane state and the drug resistance of cancer cells remain elusive. Here, we investigated the role of membrane viscosity and lipid composition in t...

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Bibliographic Details
Main Authors: Liubov Shimolina, Alexander Gulin, Nadezhda Ignatova, Irina Druzhkova, Margarita Gubina, Maria Lukina, Ludmila Snopova, Elena Zagaynova, Marina K. Kuimova, Marina Shirmanova
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
cancer
oxaliplatin
chemoresistance
microviscosity
fluorescence lifetime imaging microscopy FLIM
fluorescent molecular rotor
Online Access:https://www.mdpi.com/2072-6694/13/24/6165

Internet

https://www.mdpi.com/2072-6694/13/24/6165

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