Chronic Circadian Rhythm Disturbance Accelerates Knee Cartilage Degeneration in Rats Accompanied by the Activation of the Canonical Wnt/β-Catenin Signaling Pathway

Chronic Circadian Rhythm Disturbance Accelerates Knee Cartilage Degeneration in Rats Accompanied by the Activation of the Canonical Wnt/β-Catenin Signaling Pathway

With the gradual deepening of understanding of systemic health and quality of life, the factors affecting osteoarthritis (OA) are not limited to mechanical injury, metabolic abnormality, age and obesity, etc., but circadian rhythm, which plays a non-negligible role in human daily life. The purpose o...

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Bibliographic Details
Main Authors: Xiaopeng Song, Tianwen Ma, Hailong Hu, Mingchao Zhao, Hui Bai, Xinyu Wang, Lin Liu, Ting Li, Xuanbo Sheng, Xinyu Xu, Xinmin Zhang, Li Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
circadian rhythm disturbance
osteoarthritis
wnt/β-catenin signaling pathway
cartilage
rat
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.760988/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.760988/full

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