Replicative fitness and pathogenicity of primate lentiviruses in lymphoid tissue, primary human and chimpanzee cells: relation to possible jumps to humansResearch in context

Summary: Background: Simian immunodeficiency viruses (SIV) have been jumping between non-human primates in West/Central Africa for thousands of years and yet, the HIV-1 epidemic only originated from a primate lentivirus over 100 years ago. Methods: This study examined the replicative fitness, trans...

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Bibliographic Details
Main Authors: Denis M. Tebit, Gabrielle Nickel, Richard Gibson, Myriam Rodriguez, Nicolas J. Hathaway, Katie Bain, Angel L. Reyes-Rodriguez, Pascal Ondoa, Jonathan L. Heeney, Yue Li, Jennifer Bongorno, David Canaday, David McDonald, Jeffrey A. Bailey, Eric J. Arts
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423005315