Chemopreventive Effects of RXR-Selective Rexinoid Bexarotene on Intestinal Neoplasia of ApcMin/+ Mice

Retinoid X receptor (RXR) has been implicated in several neoplastic diseases. Previously, we have shown that RXR-α is downregulated in human and rodent colonic tumors, suggesting a potential target for colon cancer prevention (http://www.cancer.org/Cancer/ColonandRectumCancer/DetailedGuide/colorecta...

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Bibliographic Details
Main Authors: Naveena B. Janakiram, Altaf Mohammed, Li Qian, Chang-In Choi, Vernon E. Steele, Chinthalapally V. Rao
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800455