Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells.

Autophagy is an adaptive response to extracellular and intracellular stress by which cytoplasmic components and organelles, including damaged mitochondria, are degraded to promote cell survival and restore cell homeostasis. Certain genes involved in autophagy confer susceptibility to Crohn's di...

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Bibliographic Details
Main Authors: Arwa S Kathiria, Lindsay D Butcher, Linda A Feagins, Rhonda F Souza, C Richard Boland, Arianne L Theiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281932?pdf=render