Quantitative <sup>1</sup>H NMR Metabolomics Reveal Distinct Metabolic Adaptations in Human Macrophages Following Differential Activation

Quantitative <sup>1</sup>H NMR Metabolomics Reveal Distinct Metabolic Adaptations in Human Macrophages Following Differential Activation

Macrophages (M&#934;s) are phagocytic immune cells that are found in nearly all human tissues, where they modulate innate and adaptive immune responses, thereby maintaining cellular homeostasis. M&#934;s display a spectrum of functional phenotypes as a result of microenvironmental and stress...

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Bibliographic Details
Main Authors: Amanda L. Fuchs, Sage M. Schiller, Wyatt J. Keegan, Mary Cloud B. Ammons, Brian Eilers, Brian Tripet, Valérie Copié
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Metabolites
Subjects:
nmr
metabolomics
primary human macrophages
glycolysis
tca cycle
oxidative stress
kennedy pathway
immunometabolism
Online Access:https://www.mdpi.com/2218-1989/9/11/248

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https://www.mdpi.com/2218-1989/9/11/248

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