Carbodiimide-Mediated Beckmann Rearrangement of Oxyma-B as a Side Reaction in Peptide Synthesis

Carbodiimide-Mediated Beckmann Rearrangement of Oxyma-B as a Side Reaction in Peptide Synthesis

The suppression of side reactions is one of the most important objectives in peptide synthesis, where highly reactive compounds are involved. Recently, the violuric acid derivative Oxyma-B was introduced into peptide synthesis protocols as a promising additive to efficiently control the optical puri...

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Bibliographic Details
Main Authors: Andrea Orlandin, Ivan Guryanov, Lucia Ferrazzano, Barbara Biondi, Francesca Biscaglia, Claudia Storti, Marzio Rancan, Fernando Formaggio, Antonio Ricci, Walter Cabri
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
peptide
Beckman rearrangement
Oxyma-B
amino acid
coupling
racemization
Online Access:https://www.mdpi.com/1420-3049/27/13/4235

Internet

https://www.mdpi.com/1420-3049/27/13/4235

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