De novo emergence, existence, and demise of a protein-coding gene in murids

De novo emergence, existence, and demise of a protein-coding gene in murids

Abstract Background Genes, principal units of genetic information, vary in complexity and evolutionary history. Less-complex genes (e.g., long non-coding RNA (lncRNA) expressing genes) readily emerge de novo from non-genic sequences and have high evolutionary turnover. Genesis of a gene may be facil...

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Bibliographic Details
Main Authors: Jan Petrzilek, Josef Pasulka, Radek Malik, Filip Horvat, Shubhangini Kataruka, Helena Fulka, Petr Svoboda
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Biology
Subjects:
De novo
Gene
Evolution
LTR
Retrotransposon
CAG
Online Access:https://doi.org/10.1186/s12915-022-01470-5

Internet

https://doi.org/10.1186/s12915-022-01470-5

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