Molecular and metabolic regulation of immunosuppression in metastatic pancreatic ductal adenocarcinoma
Abstract Immunosuppression is a hallmark of pancreatic ductal adenocarcinoma (PDAC), contributing to early metastasis and poor patient survival. Compared to the localized tumors, current standard-of-care therapies have failed to improve the survival of patients with metastatic PDAC, that necessecita...
Main Authors: | Shailendra K. Gautam, Surinder K. Batra, Maneesh Jain |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12943-023-01813-y |
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