HMGB1: a double-edged sword and therapeutic target in the female reproductive system

HMGB1 that belongs to the High Mobility Group-box superfamily, is a nonhistone chromatin associated transcription factor. It is present in the nucleus of eukaryotes and can be actively secreted or passively released by kinds of cells. HMGB1 is important for maintaining DNA structure by binding to DN...

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Bibliographic Details
Main Authors: Yu Ren, Damin Zhu, Xingxing Han, Qiqi Zhang, Beili Chen, Ping Zhou, Zhaolian Wei, Zhiguo Zhang, Yunxia Cao, Huijuan Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1238785/full