Oxygen-Sensitivity and Pulmonary Selectivity of Vasodilators as Potential Drugs for Pulmonary Hypertension

Oxygen-Sensitivity and Pulmonary Selectivity of Vasodilators as Potential Drugs for Pulmonary Hypertension

Current approved therapies for pulmonary hypertension (PH) aim to restore the balance between endothelial mediators in the pulmonary circulation. These drugs may exert vasodilator effects on poorly oxygenated vessels. This may lead to the derivation of blood perfusion towards low ventilated alveoli,...

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Bibliographic Details
Main Authors: Daniel Morales-Cano, Bianca Barreira, Beatriz De Olaiz Navarro, María Callejo, Gema Mondejar-Parreño, Sergio Esquivel-Ruiz, Jose A. Lorente, Laura Moreno, Joan A. Barberá, Ángel Cogolludo, Francisco Perez-Vizcaino
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Antioxidants
Subjects:
pulmonary hypertension
vascular
vasodilator
oxygen-sensing
Online Access:https://www.mdpi.com/2076-3921/10/2/155

Internet

https://www.mdpi.com/2076-3921/10/2/155

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