Insilico prediction and functional analysis of nonsynonymous SNPs in human CTLA4 gene
Abstract The CTLA4 receptor is an immune checkpoint involved in the downregulation of T cells. Polymorphisms in this gene have been found to be associated with different diseases like rheumatoid arthritis, autosomal dominant immune dysregulation syndrome, juvenile idiopathic arthritis and autoimmune...
Main Authors: | Muhammad Irfan, Talha Iqbal, Sakina Hashmi, Uzma Ghani, Attya Bhatti |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-24699-0 |
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