Insilico prediction and functional analysis of nonsynonymous SNPs in human CTLA4 gene

Insilico prediction and functional analysis of nonsynonymous SNPs in human CTLA4 gene

Abstract The CTLA4 receptor is an immune checkpoint involved in the downregulation of T cells. Polymorphisms in this gene have been found to be associated with different diseases like rheumatoid arthritis, autosomal dominant immune dysregulation syndrome, juvenile idiopathic arthritis and autoimmune...

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Bibliographic Details
Main Authors:	Muhammad Irfan, Talha Iqbal, Sakina Hashmi, Uzma Ghani, Attya Bhatti
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-11-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-24699-0

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