The extracellular matrix of dystrophic mouse diaphragm accounts for the majority of its passive stiffness and is resistant to collagenase digestion

The healthy skeletal muscle extracellular matrix (ECM) has several functions including providing structural integrity to myofibers, enabling lateral force transmission, and contributing to overall passive mechanical properties. In diseases such as Duchenne Muscular dystrophy, there is accumulation o...

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Bibliographic Details
Main Authors: Ross P. Wohlgemuth, Ryan M. Feitzinger, Kyle E. Henricson, Daryl T. Dinh, Sarah E. Brashear, Lucas R. Smith
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Matrix Biology Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028523000042