The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model

Cryopreservation significantly alters the phenotype of platelets; generating distinct subpopulations, which may influence the formation of platelet leukocyte aggregates (PLA). PLAs are immunomodulatory and have been associated with transfusion-associated adverse events. As such, the aim of this stud...

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Bibliographic Details
Main Authors: Ben Winskel-Wood, Matthew P. Padula, Denese C. Marks, Lacey Johnson
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2023.2206916