miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα

miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα

Macrophages can acquire a variety of polarization status and functions: classically activated macrophages (M1 macrophages); alternatively activated macrophages (M2 macrophages). However, the molecular basis of the process is still unclear. Here, this study addresses that microRNA-181a (miR-181a) is...

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Bibliographic Details
Main Authors: Jia Bi, Xianxin Zeng, Lin Zhao, Qian Wei, Lifeng Yu, Xinnan Wang, Zhaojin Yu, Yaming Cao, Fengping Shan, Minjie Wei
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
miR-181a
C/EBPα
KLF6
macrophages
polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117300902

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http://www.sciencedirect.com/science/article/pii/S2162253117300902

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