Dissecting the mechanism of atlastin-mediated homotypic membrane fusion at the single-molecule level

Dissecting the mechanism of atlastin-mediated homotypic membrane fusion at the single-molecule level

Abstract Homotypic membrane fusion of the endoplasmic reticulum (ER) is mediated by dynamin-like GTPase atlastin (ATL). This fundamental process relies on GTP-dependent domain rearrangements in the N-terminal region of ATL (ATLcyto), including the GTPase domain and three-helix bundle (3HB). However,...

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Bibliographic Details
Main Authors: Lijun Shi, Chenguang Yang, Mingyuan Zhang, Kangning Li, Keying Wang, Li Jiao, Ruming Liu, Yunyun Wang, Ming Li, Yong Wang, Lu Ma, Shuxin Hu, Xin Bian
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46919-z

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https://doi.org/10.1038/s41467-024-46919-z

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