Enantioselective Michael Addition of Aldehydes to Maleimides Organocatalyzed by a Chiral Primary Amine-Salicylamide

Enantioselective Michael Addition of Aldehydes to Maleimides Organocatalyzed by a Chiral Primary Amine-Salicylamide

A primary amine-salicylamide derived from chiral <i>trans</i>-cyclohexane-1,2-diamine was used as an organocatalyst for the enantioselective conjugate addition of aldehydes, mainly &#945;,&#945;-disubstituted to <i>N</i>-substituted maleimides. The reaction was perfor...

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Bibliographic Details
Main Authors: Alejandro Torregrosa-Chinillach, Adrien Moragues, Haritz Pérez-Furundarena, Rafael Chinchilla, Enrique Gómez-Bengoa, Gabriela Guillena
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
organocatalysis
asymmetric synthesis
Michael addition
maleimides
aldehydes
Online Access:https://www.mdpi.com/1420-3049/23/12/3299

Internet

https://www.mdpi.com/1420-3049/23/12/3299

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